Promoting Excellence in Education, Research,
and Patient Care in the Rapidly Evolving
Management of Gastrointestinal Cancer
International Society of
Gastrointestinal Oncology
isgioEstablished 2003

2011 Gastrointestinal Oncology Conference Review

2011 Gastrointestinal Oncology Conference
September 15-17, 2011

Please click on abstract title to review abstract PDF file (opens in a new window).

Esophageal Cancer

Controversies in Adjuvant and Neoadjuvant Therapy in Gastroesophageal Cancer
David H. Ilson, MD, PhD
Memorial Sloan-Kettering Cancer Center, New York, NY


Surgery vs. Chemo-radiotherapy plus Surgery in Resectable Esophageal Cancer: A Systematic Review of Randomized Controlled Trials
Basile Njei, MD, MSPH
University of Connecticut School of Medicine, Farmington, CT, USA

Pancreatic Cancer

Metastatic Pancreatic Cancer: Are We Making Progress?
Jordan D. Berlin, MD
The Vanderbilt-Ingram Cancer Center, Nashville, TN, USA


Should Neoadjuvant Therapy for Pancreatic Cancer Adenocarcinoma be the Standard for All Patients? No!
William R. Jarnigan, MD, FACS
Memorial Sloan-Kettering Cancer Center, New York, NY, USA


Molecular Mechanisms of Resistance to STAT3 inhibition in Pancreatic Cancer
Nagaraj Nagathihalli
Departments of Surgery, University Medical Center, Nashville, TN, USA

Advanced Colorectal Cancer

Using Biomarkers to Manage Therapy in Advanced Colorectal Cancer
Wells Messersmith, MD, FACP
University of Colorado Cancer Center, Aurora, CO, USA


Identification of MicroRNAs Differentially Expressed in Normal Colon and Colon Cancer Stem Cells
Shigeo Hisamori
Stanford Institute for Stem Cell Biology and Regenerative Medicine, Stanford University, Stanford, CA, USA


The Association Between Metabolic Syndrome and Colorectal Neoplasm: A Meta-analysis of Epidemiologic Evidence
Jinjuvadia R
Detroit Medical Center, Detroit, MI, USA

Hot Topics in Gastrointestinal Oncology

The Future of Cooperative Clinical Research in Gastrointestinal Oncology
Joel E. Tepper, MD
University of North Carolina School of Medicine, Chapel Hill, NC, USA


Advances in CT Imaging of GI Malignancies
Elliot K. Fishman, MD, FACR
Johns Hopkins Hospital, Baltimore, MD, USA


S-1 Plus Intravenous and Intraperitoneal Paclitaxel for Gastric Cancer With Peritoneal Metastasis
Joji Kitayama
University of Tokyo, Tokyo, Japan


Reprogrammed Induced-Pluripotent-Stem Cells (iPSCs) Encoded With Anti-GRP78 shRNA Induces Apoptosis After a Gene-Silencing Bystander Effect Circumventing Vinorelbine-Induced Angiogenesis, and Metastatic Spread in Advanced Gastro-Intestinal Stromal Tumors (GIST)
John N Giannios
Ippokration Hospital and International Society of Molecular and Genomic Medicine and Research, and MEDICAL BIOMICS LTD, Greece

Neuroendocrine Tumors (NET)

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase III Trial (RADIANT-3) of Everolimus in Patients With Advanced Pancreatic Neuroendocrine Tumors: Updated Safety and Overall Survival Results
Jonathan R. Strosberg
H. Lee Moffitt Cancer Center & Research Institute, Tampa, FL, USA


Updated Efficacy, Safety, and Exploratory Biomarker Results From RADIANT-2: A Phase III Trial of Everolimus + Octreotide LAR vs. Placebo + Octreotide LAR in Patients With Advanced Neuroendocrine Tumors
James C. Yao
The University of Texas MD Anderson Cancer Center, Houston, TX, USA

Hepatobiliary Cancer

Systemic Therapy for Cholangiocarcinoma
Mary F. Mulcahy MD
Robert H. Lurie comprehensive Cancer Center, Northwestern University Feinberg School of Medicine, Chicago, IL, USA


Molecular Profile of Hepatocellular Carcinoma in India with Special Reference to GST gene Polymorphism
Premashis Kar
Maulana Azad Medical College, University of Delhi, India

Esophageal/Gastric Cancer

Concurrent Radiotherapy and Capecitabine as Adjuvant Treatment after Surgery for Gastric Cancer
Abbas H
Department of Radiation Oncology, South Egypt Cancer Institute, Assiut University, Egypt


Efficacy of Endoscopic Submucosal Dissection for Early Gastric Neoplasms: Analysis of 1123 Lesions
Tatsuya Toyokawa
Department of Gastroenterology, National Hospital Organization Fukuyama Medical Center, Fukuyama, Japan


Erlotinib and Radiation Therapy for Elderly Patients With Esophageal Cancer: Clinical and Correlative Results From a Prospective Multicenter Phase II trial
R Chhatrala
University at Buffalo


Esophagectomy for Esophageal Cancer: Results of the Last Decade From a Tertiary Care Center of North India
Amit Javed
All India Institute of Medical Sciences, Ansari Nagar, New Delhi


Hyperbaric Oxygen Therapy: An Adjuvant Treatment Modality for Chemo-Radiation Induced Hemorrhagic Gastritis
Dr Amit Javed
All India Institute of Medical Sciences, Ansari Nagar, New Delhi


Topography of Chronic Active Gastritis Among  Helicobacter Pylori Positive Patients in Bangladesh
Hafeza Aftab
Dhaka Medical College, Dhaka, Bangladesh

Pancreatic Cancer

Comparison of Efficacy Between Gemcitabine/Erlotinib (GE) and Gemcitabine/Capecitabine (GX) in Unresectable Pancreatic Cancer: Retrospective, Single Center Experience, Final Report
Myung- Ah Lee
Division of Medical Oncology, Hepato-Biliary-Pancreatic Cancer Center, Seoul St. Mary’s Hospital, College of Medicine, Catholic University of Korea, Seoul, Korea 


Etiology of Enlarged Heart: A Rare Pancreatic Tumor
Divey Manocha
SUNY Upstate Medical University, Syracuse, NY, USA


Genetic Alterations of Pancreatic Cancer In North Indian Population
Sunil K Polipalli
Department of Medicine, Maulana Azad Medical College, University of Delhi, New Delhi, India


LNA-Modified Oligonucleotides Targeting mRNA of DICER in Pegylated Colloidal Nanoparticles With Linked Αbs Against CD44 on Pancreatic Cancer Stem Cells (PCSCs) Induces PCD After Inhibition Of Oncomirs Leading to Downregulation of Antiapoptotic Oncogenes That Interact With Their 3'UTRs and Inhibition of DNA Hypermethylation Leading to Activation of Apoptotic Tumor Suppressor Genes
Dr John N Giannios
Head of Translational Medicine, Erasinio Oncology Hospital, Athens, Greece

Colorectal Cancer

A Retrospective Single Study Analysis of Survival Outcomes in Metastatic Colorectal Cancer
F McCarthy
St Bartholomew’s Hospital, West Smithfield, London, United Kingdom 


Response To Systemic Chemotherapy With Cetuximab in KRAS Mutated Patients With Liver Metastases From Colorectal Cancer
Petrovic Z
Dept. of GI Oncology, Clinic of gastroenterology, VMA, Belgrade, Serbia


Single Incision Laparoscopic Right Hemicolectomy in Advanced Colon Cancer
Koo Yong Hahn, MD
Department of Surgery, Seongnam Central Hospital, Jungwon-gu, Seongman, South Korea


The Association between Helicobacter pylori infection and Colorectal Cancer: A Meta-Analysis of Epidemiologic Evidence
Basile Njei, MD, MSPH
University of Connecticut School of Medicine, Farmington, CT, USA


A Superficial Colon Tumor Model Involving Subcutaneous Colon Translocation and Orthotopic Transplantation of Green fluorescent Protein-Expressing Human Colon Tumor
Heiying Jin
National Center of Colorectal Surgery, The 3rd affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, P.R. China


Expression and Clinical Significance of Notch Signaling Genes in Colorectal Cancer
Hei-Ying JIN
National center of colorectal surgery, The 3rd affiliated Hospital of Nanjing University of Traditional Chinese Medicine, Nanjing, China


Pilot Study of Short-Course Preoperative Radiation Therapy using Intensity Modulated Radiation Therapy (IMRT) for Patients With Rectal Cancer
Aaron Rickles, MD
Division of Colorectal Surgery, University of Rochester Medical Center


Assessment of a novel VEGF targeted agent using patient-derived tumor tissue xenograft models of colon carcinoma with lymphatic and hepatic metastases
Li Song Teng
of Surgical Oncology, First Affiliated Hospital, College of Medicine, Zhejiang University, Hangzhou, Zhejiang, China

Neuroendocrine Tumors (NET)

Temozolomide and Thalidomide for Neuroendocrine Tumors: A Retrospective Report
Ramakrishna Thotakura
Department of Medicine, State University of New York, Buffalo, NY 

Hepatobiliary Cancer

Eradication of Unresectable Chemo/Radioresistant Hilar Cholangiocarcinoma With Gene-Modified Cellular Vaccine (GMCV) Composed of Autologous Adipose-Derived Mesenchymal Stem Cells (AADMSCs) Transfected With Lipid-cation Hsp70 Activated Innate and Adaptive Immunity, and Induced SecondaryNecrosis Leading to a Lethal Bystander Effect
Dr John N Giannios
Head of Translational Medicine, Erasinio Oncology Hospital, Athens, Greece 


Human APEndonuclease (APE1/ref-1), a DNA Repair Enzyme, in Gall Bladder Cancer and its Correlation With Tumor Infiltration and Perineural Invasion
Prashant Chandra Das
Department of General Surgery, IMS, BHU, Varanasi, India 


Phase I Adjuvant Trial of Sorafenib in Hepatocellular Carcinoma (HCC) Patients After Orthotopic Liver Transplantation (OLT)
Ning Jia
Department of Medical Oncology, Peking Union Medical College Hospital, Peking Union Medical College and Chinese Academy of Medical Sciences , Tsinghua University Health System, Beijing
University of Washington, Seattle, WA, USA  

Hot Topics

HER2 Status in Gastric and Gastroesophageal Junction Adenocarcinoma: Analysis of 726 Consecutive Cases in Four Chinese Hospitals
Dan Huang
Department of Pathology, Fudan University Shanghai Cancer Center
Department of Oncology, Shanghai Medical College, Fudan University 

Localized/Adjuvant Colorectal Cancer

Lymph Node Correlations and Thresholds in Colorectal Cancer Specimens
Jatinder S. Minhas, BSc (Hons)
Norwich Medical School, Norwich UK