Promoting Excellence in Education, Research,
and Patient Care in the Rapidly Evolving
Management of Gastrointestinal Cancer
International Society of
Gastrointestinal Oncology
isgioEstablished 2003

2007 Gastrointestinal Oncology Conference Review

2007 Gastrointestinal Oncology Conference
September 27-29, 2007

Please click on abstract title to review abstract PDF file (opens in a new window).

Session I: Esophageal Cancer
Esophageal Cancer
Brian Reid
Is Radiation Therapy Needed in the Treatment of Gastroesophageal Junction Adenocarcinoma?
Joel Tepper

Surgery for Esophageal Cancer
Thomas A. D'Amico, MD

Proffered Papers

The Significance of Thromboembolic Phenomena Occurring Before and During Chemoradiotherapy for Localized Carcinoma of the Esophagus and Gastroesophageal Junction
Eric D. Tetzlaff

Oxaliplatin Induces the Expression of Genes Involved in Capecitabine Activation: Preliminary Results of a Phase I Pharmacodynamic Study in Esophageal Cancer
Sanjay Vinjamaram

Session 2: Pancreatic Cancer
Emerging Molecular Biology of Pancreatic Cancer
Ralph H. Hruban, MD
Proffered Papers
TFF1 Is Overexpressed Early in Pancreatic Cancer and Stimulates Cancer Cell Invasion and Stromal Cell Growth and Migration
T. Arumugam
Phase I Study of Erlotinib, Bevacizumab, and Gemcitabine in Patients With Advanced Pancreatic Cancer
C. Gomez-Martin
Tissue Transglutaminase Downregulation Potentiates Gemcitabine Efficacy and Blocks Pancreatic Cancer Growth in vivo
S. Guha
Novel Use of Focal High-Dose IMRT for Borderline Resectable Pancreatic Cancer
Stephen H. Settle
Session 3: Advanced Colorectal Cancer

Curable Metastatic Colon Cancer
John Marshall, MD

Proffered Papers

A Randomized Phase II Trial of Irinotecan With Hyaluronan (HYCAMP) versus Irinotecan Alone as Treatment for Patients With Metastatic Colorectal Cancer Who Have Failed 5-Fluorouracil-Based Chemotherapy
P. Gibbs

Capecitabine and Oxaliplatin (CAPOX) Plus Cetuximab in Patients With Metastatic Colorectal Carcinoma Who Progressed After Oxaliplatin-Based Chemotherapy
Z. Petrovic

Galectin-3 Mediates Nuclear b-catenin Accumulation and Wnt Signaling in Human Colon Cancer Cells Through Regulation of  GSK-b Activity
Shumei Song

Price Tag on Progress: Rising Chemotherapy Cost for Colorectal Cancer — Evidence From Medicare Claims Analysis
Jue Wang, MD
Session 4: Hepatobiliary Cancer
Proffered Papers

Tumor Growth in the Liver Depends on Antigen Load and Immunologic Ignorance
Diego Avella, MD

Session 5: Emerging Science

Recent Advances in Gastrointestinal Cancer Stem Cells
Lopa Mishra, MD

Integrative Functional Genomics to Decode Human Cancer Signatures
Ju-Seog Lee, PhD

Genomic Classifiers in Colon Cancer: Clinical Utility
Daniel Sargent, PhD

Session 6: Adjuvant Colon Cancer

Individualization of Therapy Based on Clinical and Molecular Parameters
Heinz-Josef Lenz, MD

Proffered Papers

Prevention of Oxaliplatin-Induced Neurotoxicity With Ca2+/Mg2+ Infusions: Preliminary Results of the NEUROXA Randomized Trial in Patients With Colorectal Cancer (CRC) Receiving The FOLFOX4 Regimen
E. Gamelin

Survival Analysis of 150 Metastatic Mid-Gut Carcinoid Tumors
Jonathan Strosberg, MD

Adjuvant Treatment of Colorectal Cancer
Alfredo Carrato, MD, PhD

Session 7: Gastric Cancer

Localized Gastric Cancer: Approaches in Japan
Mitsuru Sasako, MD, PhD

Advanced Gastric Cancer: An Update and Future Directions
Al B. Benson III, MD, FACP

Proffered Papers

Randomized Phase III Study of S-1 Alone versus S-1 Plus Cisplatin (SPIRITS: TS-1 Advanced Gastric Cancer Clinical Trial Group
M. Takagi

A Phase II Study of Biweekly Dose-Intensified Oral Capecitabine Plus Irinotecan (bXELIRI) for Patients With Advanced or Metastatic Gastric Cancer
Yeul Hong Kim

Neoadjuvant Radiochemotherapy for Elderly Patients With Locally Advanced Gastric Cancer
Rodica Anghel MD, PhD

Session 8: Rectal Cancer

Defining Preoperative Treatment Strategies in T3 Rectal Cancer
J.F. Bosset

Preoperative Therapy for Rectal Cancer
Bruce Minsky, MD

Proffered Papers

Sacral Insufficiency Fractures After Preoperative Chemoradiation for Rectal Cancer
Michael P. Herman

Multi-Targeted siRNA Against UbcH5, c-Src, and HSP90 Combined With Cetuximab Circumvented Oncogene Addiction, Transactivation, and Acquired Resistance Due to EGFR Ubiquitination, and Mutations/Deletions in the Kinase Domain of EGFR in mCRC
J. Giannios

Abstracts Selected for Poster Presentations
Esophageal Cancer

Lymphovascular Invasion as a Tool to Further Subclassify T1b Esophageal Adenocarcinoma
Putao Cen, MD

Comparison of the Outcomes of Patients With Localized Esophageal Carcinoma Receiving Bimodal versus Trimodal Therapy
H. Javeri

Pancreatic Cancer

WP1066, a Potent Inhibitor of Jak2/STAT3 Pathway, Inhibits Pancreatic Cancer Growth Both in vitro and in vivo
A. Chakraborty

Exciting Results With Weekly “Metronomic Dosing” of Paclitaxel, Oxaliplatin, Leucovorin, and 5-Fluorouracil (POLF) in the Treatment of Metastatic Pancreatic Cancer
Ben M. Chue, MD

CXCL8 and CXCL12 Cooperatively Promote Invasion and Angiogenesis of Pancreatic Cancer
Y. Matsuo

Prognostic Factors and Clinicopathologic Characteristics of Carcinoma of Ampulla of Vater
Merve Pamukcuoglu

Adrenomedullin is an Autocrine Regulator via the ADMR Receptor of Cancer, Stromal, and Endothelial Cells in Pancreatic Tumors
Vijaya Ramachandran

Neutrophil Gelatinase-Associated Lipocalin: A Novel Suppressor of Invasion and Angiogenesis in Pancreatic Cancer
Z. Tong

Advanced Colorectal Cancer

Epoetin Alfa 80,000 U Every 2 Weeks vs. 40,000 U Weekly for Chemotherapy-Induced Anemia: Colorectal Cancer Patient Subset From a Randomized Clinical Study
Tomek Szczudlo, MD

Systematic Survey of Therapeutic Trials for Metastatic Colorectal Cancer: Room for Improvement in the Critical Pathway
Scott Kopetz, MD

Hepatobiliary Cancer

Contrast-Enhanced Magnetic Resonance Imaging: A Reliable Method to Evaluate Tumor Progression/Regression in a Murine Model of Hepatocellular Cancer
Luis J. Garcia, MD

Emerging Science

Analysis of and Improvements in Chemotherapy Approaches for Gastrointestinal Cancer at Kitasato University East Hospital in Japan, Based on Comparison With the University of Texas M. D. Anderson Cancer Center in the United States
Mizue Shida, BS

Gastric Cancer

Overexpression of Transcription Factor FoxM1b Promotes Human Gastric Cancer Angiogenesis and Metastasis and Predicts Poor Patient Survival
Qiang Li

Rectal Cancer

Is Transanal Endoscopic Microsurgery Adequate in the Removal of Rectal Lesions?
A.J. Ky